Biostic BacterimiaWhen the BiOstic® Bacteremia DNA Isolation kit was originally designed, it was optimized for the extraction of bacterial DNA from infected blood. However, it has turned out to be useful for so much more. Bacteremia is the presence of bacteria in the blood and under normal circumstances blood should be sterile, but with the insertion of a catheter into the body or through an open wound, bacteria can gain entry and take hold. Even a small numbers of bacteria can be a real problem...

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Posted in Technical Tips By Michelle Tetreault Carlson

Vampire Ventures

10/30/2014 4:16 PM

Blood contains a mixture of plasma, red and white cells and platelets.  It is a unique beast among sample types, because while the quantity of nucleic acids in blood is copious, this genetic gold mine bathes inside a complex soup of cellular debris and protein. These contaminants can interfere with downstream PCR and sequencing.  It is the hemoglobin in particular, within the red cells, which causes major issues in DNA/RNA contamination and PCR inhibition.

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Posted in Technical Tips By Mo Bio